To determine the etiologies of AFI among children and adolescents (2-17 years) and adults (18+ years) attending selected health facilities in Liberia to inform public health programs at these facilities including capacity development to identify, monitor, and assess pathogens of potential public health importance, programmatic improvement for patient care and treatment, and resource allocations.
The AFI surveillance Liberia, investigates for over 28 pathogens (Bacteria, Viruses, and protozoa) associated with febrile illnesses using the TaqMan Array Card (TAC) quantitative polymerase chain reaction (qPCR).
Surveillance activities under the AFI project are currently at Redemption Hospital and Star of the Sea Health Centre where over 3000 patient enrollments detecting over 9 different pathogens dominated by Plasmodium/Plasmodium falciparum. Surveillance activities under the AFI surveillance, Liberia has augmented Liberia’s diagnostic capacities immensely through the emergency use of TAC where pathogen diagnostic capacities are limited or for pathogen of unknown etiology causing outbreaks in Liberia.
The AFI surveillance, Liberia in response support to the SARS-CoV-2 pandemic in Liberia also sought to use existing AFI surveillance systems for epidemiological and virologic surveillance for COVID-19. The integration of COVID-19 in existing AFI surveillance project support emergency and high-priority investigations through leveraging existing systems and available staff, material, supplies, reagents, and testing processes of samples its two surveillance sites (Redemption Hospital and Star of the Sea Health Centre). The objective of integration of COVID-19 activities into the AFI surveillance project, Liberia received administrative approval from the Incident Management System, Ministry of Health, and the National Public Health Institute of Liberia.